Praise The Lord Saints!! Praise The Lord Everyone!! I have a very important question to ask everyone. What is the definition of a depraved mind? A depraved mind is as follows: The condition of mind described as depravity of mind is characterized by an inherent deficiency of moral sense and integrity. It consists of evil, corrupt and perverted intent which is devoid of regard for human dignity and which is indifferent to human life. It is a state of mind outrageously horrible or inhuman.